Figure 2
Dynamic response of the network after a perturbation in X 3 The response is shown as relative deviation from steady state. The guidelines proposed by Vance et al. [8] indicate that X1 and X4 precede X2 and X5 because they reach their maximum deviation earlier and the maximal values are larger than those of X2 and X5. All variables respond in a positive manner, which implies either a mass transfer or positive modulation (activation). The system determined from this analysis is essentially the same as in Figure 1a. The only relationship missed is the effect of X2 on the production and degradation of X3.