Table 4 Binding interactions for Rb1 and P16-INK4A
Receptor protein | Interacting protein | Interactions (Receptor residue →Interacting protein residue) | Bond distance |
|---|---|---|---|
P16-INK4A | CDK4 | Arg47:NH2 →Thr 104:OG1 | 3.6 |
Arg 80:NH2 → Trp 106: O | 2.2 | ||
Met 1: N →Val 9: O | 3.4 | ||
Cys72:N →Thr104:O | 2.9 | ||
RB1 | E2F1 | Glu 864:O →Gln 290:2HEZ | 2.5 |
Ser 567:OG →Arg 22:1HH1 | 2.7 | ||
Asp 36: OD2 →Lys 89:1HZ | 2.2 | ||
Arg 861:2HHZ →Thr 285:OG1 | 1.9 |