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Figure 4 | Theoretical Biology and Medical Modelling

Figure 4

From: Fluctuations in Tat copy number when it counts the most: a possible mechanism to battle the HIV latency

Figure 4

Phase diagrams for the dose reduction coefficient. The panels (a-c) and (e-f) depict contour plots of the dose reduction coefficients and respectively. For both quantities three hyperplanes are considered: (a) and (d) for (v=v R ,u,ϵ), (b) and (e) for (v,u=u R ,ϵ), (c) and (f) for (v,u,ϵ=ϵ R ). The position of the resistor model operating point is marked by the white circle. In all plots for lighter (darker) regions the dose reduction coefficient has relatively small (large) values. In lighter (darker) regions the noise-based treatment is (not) advantageous over noise free treatment. For operating points that are located in light regions the noise-based treatment can bring relatively large dosage reductions while in the dark regions it might not be that advantageous if compared to a noise-free treatment.

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