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Table 1 Transition rates for simulation studies of time activity and time‐concentration activity models

From: Stochastic time‐concentration activity models for cytotoxicity in 3D brain cell cultures

   A( t)   A( t,c)
Scenario δ Y α X Y α Y X δ Y i α X Y i δ Y s α X Y s
‘Fast low stress’ 10 10 30
‘Fast high stress’ 35 15 0
‘Normal low stress’ 3.5 2 4.5
‘Normal high stress’ 6 4 0
‘Slow low stress’ 0.5 0.5 0.5
‘Slow high stress’ 1.0 0.5 0
‘Different parameters’ 1.1 3.3 1.7 5.1
‘Identical intercept’ 2.2 2.2 5.1 1.7
‘Identical slope’ 1.1 3.3 8.4 8.4
’Identical rates’ 2.2 2.2 3.4 3.4
  1. Transition rates are denoted by δ Y (c)≡δ Y , α X Y (c)≡α X Y , α Y X (c)≡α Y X in [time] −1 for the time activity model and by δ Y (c)=δ Y i +c·δ Y s , α X Y (c)=α X Y i +c·α X Y s for the time‐concentration activity model in [time] −1 and [time · concentration] −1 for intercept and slope parameters, respectively.