Skip to main content

Table 1 Transition rates for simulation studies of time activity and time‐concentration activity models

From: Stochastic time‐concentration activity models for cytotoxicity in 3D brain cell cultures

  

A( t)

 

A( t,c)

Scenario

δ Y

α X Y

α Y X

δ Y i

α X Y i

δ Y s

α X Y s

‘Fast low stress’

10

10

30

‐

‐

‐

‐

‘Fast high stress’

35

15

0

‐

‐

‐

‐

‘Normal low stress’

3.5

2

4.5

‐

‐

‐

‐

‘Normal high stress’

6

4

0

‐

‐

‐

‐

‘Slow low stress’

0.5

0.5

0.5

‐

‐

‐

‐

‘Slow high stress’

1.0

0.5

0

‐

‐

‐

‐

‘Different parameters’

‐

‐

‐

1.1

3.3

1.7

5.1

‘Identical intercept’

‐

‐

‐

2.2

2.2

5.1

1.7

‘Identical slope’

‐

‐

‐

1.1

3.3

8.4

8.4

’Identical rates’

‐

‐

‐

2.2

2.2

3.4

3.4

  1. Transition rates are denoted by δ Y (c)≡δ Y , α X Y (c)≡α X Y , α Y X (c)≡α Y X in [time] −1 for the time activity model and by δ Y (c)=δ Y i +c·δ Y s , α X Y (c)=α X Y i +c·α X Y s for the time‐concentration activity model in [time] −1 and [time · concentration] −1 for intercept and slope parameters, respectively.
Back to article page

Theoretical Biology and Medical Modelling

ISSN: 1742-4682