The design of a new truncated and engineered alpha1-antitrypsin based on theoretical studies: an antiprotease therapeutics for pulmonary diseases

Table 1 Engineered, truncated α1AT structures

Structure	Number of residue	Molecular weight	Mutation sites	N-terminal deletion
α1AT1	350	39342.3	M351V, M358L, M226L	46 aa
α1AT2	396	44560.8	M351V, M358L, M226L, N83Q, N243Q	_
α1AT3	350	39328.2	M351V, M358L, M226L	46 aa
α1AT4	396	44560.8	M351V, M358L, M226L, N46Q, N243Q	_
α1AT5	396	44532.8	M351V, M358L, M226L	_

ISSN: 1742-4682