Table 5 Parameters of AutoDock used in docking analysis
Lead compounds | Centre | Size (X-axis* Y-axis* Z-axis) | Rate of gene mutation | Rate of crossover | Binding affinity (Kcal/mol) | ||
|---|---|---|---|---|---|---|---|
X-axis | Y-axis | Z-axis | |||||
A | 5.52 | 61.778 | 35.2 | 40*40*40 | 0.02 | 0.8 | −4.8 |
B | 5.846 | 61.933 | 35.423 | 40*40*40 | 0.02 | 0.8 | −4.9 |
C | 5.846 | 61.933 | 35.423 | 40*40*40 | 0.02 | 0.8 | −8.6 |
D | 5.846 | 61.933 | 35.423 | 40*40*40 | 0.02 | 0.8 | −9.9 |