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Table 2 Secondary infection risks (SIR) during contact tracing and chemoprophylaxis against influenza A (H1N1-2009)

From: Effectiveness of antiviral prophylaxis coupled with contact tracing in reducing the transmission of the influenza A (H1N1-2009): a systematic review

Authors

Ages traced

No. subjects traced

Secondary cases with prophylaxis

SIR % (95% CI) with prophylaxis

No. w/o prophylaxis

Secondary cases w/o prophylaxis

SIR % (95% CI) w/o prophylaxis

Secondary case ascertainment

Baz et al. [18]

15, 18, 50 and 59 y/o

4

1

25.0 (0, 67.4)

0

0

NC

RT-PCR

Calatayud et al. [19]

N/A

2042

0

0

N/A

N/A

N/A

RT-PCR

CDC [20]

N/A

43

0

0

N/A

N/A

N/A

ILI

CDC [20]

N/A

284

6

2.1 (0.4, 3.8)

16

0

0

ILI

CDC [20]

N/A

983

176

17.9 (15.5, 20.3)

N/A

N/A

N/A

ILI

Fallo et al. [21]

N/A

266

29

10.9 (7.2, 14.7)

31

12

38.7 (21.6, 55.9)

ARI/ILI

France et al. [22]

Median 45 y/o (range: 0–91 y/o)

50

2

4.0 (0, 9.4)

651

76

11.7 (9.2, 14.1)

ILI

Iioka et al. [23]

N/A

49

6

12.2 (3.1, 21.4)

0

0

NC

RDT/RT-PCR

Jackson et al. [24]

N/A

9.7†

3.6†

37.1 (6.7, 67.5)

69.3†

11.5†

16.6 (7.8, 25.4)

Serology

Komiya et al. [6]

Median 43 y/o (quartiles: 0–82)

333

2

0.6 (0, 1.4)

46

12

26.1 (13.4, 38.8)

RT-PCR

Kute et al. [25]

40 y/o

1

0

0

0

0

NC

ILI

Leung et al. [26]

N/A

64

0

0

141

12

8.5 (3.9, 13.1)

RT-PCR

Lisena et al. [27]

Not specified

5

0

0

1

1

100 (NC)

RT-PCR

Maltezou et al. [28]

Median 11 days (0–27 days)

13

0

0

0

0

NC

ILI

Morgan et al. [29]

N/A

92

18

19.6 (11.5, 27.7)

143

12

8.4 (3.8, 12.9)

ARI/ILI/RT-PCR

Pannaraj et al. [30]

2–343 d/o

21

0

0

0

0

NC

ILI

Tsagris et al. [31]

Below 1 y/o

20

1

5.0 (0, 14.6)

0

0

NC

RT-PCR

van Gemert et al. [32]

1–74 y/o

57

1

1.8 (0, 5.2)

65

17

26.2 (15.5, 36.8)

ILI

Weston et al. [33]

N/A

83

2

2.4 (0, 5.7)

0

0

NC

Non Specified

  1. 95% CI, 95 percent confidence interval; RDT, rapid diagnostic testing; ILI, influenza-like illness (fever plus cough or sore throat); RT-PCR, reverse transcriptase polymerase chain reaction; N/A, not available; NC, not calculable; †figure with decimal point was used as it was weighted by an inverse of the probability of being sampled to account for oversampling of households with suspected transmission.