Figure 1
From: On the role of resonance in drug failure under HIV treatment interruption
Simulation of viral load and the effect of drug interruption over time (A) and as a function of the period of STI (B). Shaded areas represent the intervals of time on treatment, modelled as a decrease by 30 % in β and k as in[12]. Red and blue are the patients A and B from[12]. Patient A: λ=20, d=0.02, a=0.4, u=4.0, β=5 10−5, k=100, and patient B, as A except β=8 10−5. The level of resonance (R) is defined by the ratio of a (the maximum value attained by the virus population) and b (the viral set point).