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Table 1 Baseline and kinetic data for injected glucose and fluid during an intravenous glucose tolerance test before and after hip replacement surgery in 22 patients

From: Plasma volume expansion from the intravenous glucose tolerance test before and after hip replacement surgery

 

Before surgery

After surgery

Statistics

Plasma glucose, baseline (mmol/L)

5.6 (5.3-5.8)

6.0 (5.8-6.5)

P < 0.001

B-Hb concentration (g/dL)

12.4 (12.0-13.3)

10.0 (9.0-10.6)

P < 0.001

Glucose kinetics

   

 Vd (L)

12.7 (10.2-15.6)

14.0 (12.1-14.8)

NS

 CL (ml/min)

325 (272–385)

260 (220–306)

P < 0.02

 T1/2 (min)

30 (19–34)

36 (30–45)

P < 0.02

Fluid kinetics, no glucose uptake

   

 V (L)

2.94 (2.17-3.60)

2.83 (2.62-3.22)

NS

 CL (ml/min)

200 (70–261)

93 (64–189)

P < 0 001

 T1/2 (min)

12 (5–30)

21 (10–33)

P < 0.001

Fluid kinetics, with glucose uptake

   

 V (L)

2.79 (2.50-3.42)

2.73 (2.40-3.05)

NS

 CL (ml/min)

37 (−7 to 165)

9 (−14 to 55)

P < 0.02

  1. Data is the median and 25th-75th percentile limits.
  2. The Wilcoxon matched-pair test was used for statistics. NS = not statistically significant.
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Theoretical Biology and Medical Modelling

ISSN: 1742-4682