From: Identification of novel PTPRQ phosphatase inhibitors based on the virtual screening with docking simulations
Compounds
% inhibition at 100 μM for PTPRQ
% inhibition at 100 μM for PTPRO
1
71.1 ± 0.8
94.4 ± 0.5
2
57.7 ± 0.4
94.2 ± 1.5
3
50.9 ± 2.2
48.7 ± 2.1
4
82.6 ± 0.2
95.0 ± 3.5
5
62.5 ± 1.6
95.0 ± 0.8
6
57.0 ± 2.1
81.2 ± 0.9