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Table 2 Comparison of the inhibitory activities of 1–6 for PTPRQ and PTPRO

From: Identification of novel PTPRQ phosphatase inhibitors based on the virtual screening with docking simulations

Compounds

% inhibition at 100 μM for PTPRQ

% inhibition at 100 μM for PTPRO

1

71.1 ± 0.8

94.4 ± 0.5

2

57.7 ± 0.4

94.2 ± 1.5

3

50.9 ± 2.2

48.7 ± 2.1

4

82.6 ± 0.2

95.0 ± 3.5

5

62.5 ± 1.6

95.0 ± 0.8

6

57.0 ± 2.1

81.2 ± 0.9