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Table 2 Comparison of the inhibitory activities of 1–6 for PTPRQ and PTPRO

From: Identification of novel PTPRQ phosphatase inhibitors based on the virtual screening with docking simulations

Compounds % inhibition at 100 μM for PTPRQ % inhibition at 100 μM for PTPRO
1 71.1 ± 0.8 94.4 ± 0.5
2 57.7 ± 0.4 94.2 ± 1.5
3 50.9 ± 2.2 48.7 ± 2.1
4 82.6 ± 0.2 95.0 ± 3.5
5 62.5 ± 1.6 95.0 ± 0.8
6 57.0 ± 2.1 81.2 ± 0.9