Figure 1From: Rate-dependent Ca2+ signalling underlying the force-frequency response in rat ventricular myocytes: a coupled electromechanical modeling studyCaM-CaMKII-CaN pathways. Reaction Maps. (A) Cooperative binding of 2 C a2+ to CaM sequentially to the C and then N-terminal hands along with binding of CaM buffers; (B) Probabilistic model of CaMKII subunit switching; (C) Reaction map for reversible binding of CaM, Ca 2CaM and Ca 4CaM to CaN.Back to article page