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Table 1 Frequency dependence of intracellular cAMP concentration

From: Rate-dependent Ca2+ signalling underlying the force-frequency response in rat ventricular myocytes: a coupled electromechanical modeling study

Stimulation frequency (Hz)

Intracellular cAMP concentration (μM)

0.50 - 1.67

2.67 δ

2.50

3.00

2.86

3.19

3.33

3.45

4.00

3.85

5.00

4.67

5.71

5.58

6.67

18.06

8.00

24.58

10.00

27.03

12.00

29.17

  1. δ- Value used under basal conditions. Intracellular cAMP concentration corresponding to maximal β-adrenergic stimulation at various stimulation frequencies used in the model (based on Equation 2, Demir et al. [25]).