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Table 1 Frequency dependence of intracellular cAMP concentration

From: Rate-dependent Ca2+ signalling underlying the force-frequency response in rat ventricular myocytes: a coupled electromechanical modeling study

Stimulation frequency (Hz) Intracellular cAMP concentration (μM)
0.50 - 1.67 2.67 δ
2.50 3.00
2.86 3.19
3.33 3.45
4.00 3.85
5.00 4.67
5.71 5.58
6.67 18.06
8.00 24.58
10.00 27.03
12.00 29.17
  1. δ- Value used under basal conditions. Intracellular cAMP concentration corresponding to maximal β-adrenergic stimulation at various stimulation frequencies used in the model (based on Equation 2, Demir et al. [25]).