From: Rate-dependent Ca2+ signalling underlying the force-frequency response in rat ventricular myocytes: a coupled electromechanical modeling study
Stimulation frequency (Hz)
Intracellular cAMP concentration (μM)
0.50 - 1.67
2.67 δ
2.50
3.00
2.86
3.19
3.33
3.45
4.00
3.85
5.00
4.67
5.71
5.58
6.67
18.06
8.00
24.58
10.00
27.03
12.00
29.17