Table 1 Putative MK5 inhibitors selected on basis of their IC50 value
Structure | Chemical comp. | ChEMBL comp id. | Pubmed id. | IC50 (nM) |
|---|---|---|---|---|
| C21H18N4OS | CHEMBL1231206 | 20237073 | 5 |
| C24H23N5O2 | CHEMBL461139 | 18945615 | 24 |
| C23H23N5O2 | CHEMBL461140 | 18945615 | 28 |
| C21H16N4O | CHEMBL226403 | 17480064 | 81 |
| C18H15N3O | CHEMBL388566 | 17480064 | 140 |
| C18H14FN3O | CHEMBL226471 | 17480064 | 210 |
| C12H11N3O | CHEMBL225519 | 17480064 | 500 |
| C30H28O8 | CHEMBL34241 | 10998351 | 1900 |
| C13H14N2O3 | CHEMBL395157 | 17570666 | 19000 |
| C18H16N6S2 | CHEMBL34704 | 10998351 | 50000 |
