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Table 1 Putative MK5 inhibitors selected on basis of their IC50 value

From: Homology modeling and ligand docking of Mitogen-activated protein kinase-activated protein kinase 5 (MK5)

Structure Chemical comp. ChEMBL comp id. Pubmed id. IC50 (nM)
C21H18N4OS CHEMBL1231206 20237073 5
C24H23N5O2 CHEMBL461139 18945615 24
C23H23N5O2 CHEMBL461140 18945615 28
C21H16N4O CHEMBL226403 17480064 81
C18H15N3O CHEMBL388566 17480064 140
C18H14FN3O CHEMBL226471 17480064 210
C12H11N3O CHEMBL225519 17480064 500
C30H28O8 CHEMBL34241 10998351 1900
C13H14N2O3 CHEMBL395157 17570666 19000
C18H16N6S2 CHEMBL34704 10998351 50000