Figure 2
From: Surgical inflammatory stress: the embryo takes hold of the reins again
Surgical stressful inflammatory response. The host organism provides the inflamed interstitium molecules and cells by up-regulating a neurogenic-related axis (NA), a bone marrow-related axis (BMA) and a gut-liver axis (GLA). The molecular and cellular infiltration of the “endothelial egg” induces the development of a new tissue or organ using inflammatory mechanisms. BCE: blood capillary endothelium; C: coagulation; E: epithelium; ESC: endothelial precursor cell; F: fibroblast; HEVE: high endothelial venule endothelium; HSC: hemopoietic stem cell; LE: lymphatic endothelium; Leu: leukocytes; M: microbiome; MSC: mesenchymal stem cell; PCVE: postcapillary venule endothelium; SC: resident stem cell; SG: suprarenal gland.