Terms | Description | Reference formulation |
---|---|---|
U M | Therapeutic efficiency factor of Chemotherapy | U M  = {1 − exp(−M)} [Eq. (10)] |
U L | Therapeutic efficiency factor of Cytotoxic T-lymphocytes | U L  = d Ll/(s Tl + Ll) [Eq. (10)] |
U I | Therapeutic efficiency factor of Interleukin-2 | U I  = p I LI/(g I  + I) [Eq. (27)] |
b T | Total tumour cell lysis effect from the two cytotoxic agents, Chemotherapy (temozolomide) and Cytotoxic T-cells | b T  = U M gT 1 + U L gT 2 [Eq. (12)] |
b L | Total cytotoxic T-cell activation effect from the two Immuno-modulating agents, Interleukin and Tumour-infiltrating lymphocyte | b L  = U I  + v L [Eq. (29)] |