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Figure 1 | Theoretical Biology and Medical Modelling

Figure 1

From: In-silico models of stem cell and developmental systems

Figure 1

An example of the genetic regulatory network in pancreatic development. Interactions between cell-extrinsic cues (red arrows) and cell-intrinsic molecules (black arrows) mediate cellular differentiation. Endoderm cells (red) give rise to a pancreas progenitor cell (green) that enter the Notch signaling stage (yellow) to determine endocrine (purple) or exocrine (blue) fate. Endocrine cells then commit to a beta or alpha fate (reproduced from [6])).

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