Table 1 Passive parameters and ionic conductance of channels for all compartments of pyramidal cells
From: The role of the entorhinal cortex in epileptiform activities of the hippocampus
Mechanism | Soma | Prox dend | Med dend | Dist dend |
|---|---|---|---|---|
Cm, μF/cm2 | 1 | 2 | 2 | 2 |
Rm, Ωcm2 | 60000 | 30000 | 30000 | 30000 |
Ra, Ωcm | 200 | 200 | 200 | 200 |
Leak conductance [S/cm2] | 0.000017 | 0.000033 | 0.000033 | 0.000033 |
Sodium conductance [S/cm2] | 0.035 | 0.035 | 0.035 | 0.035 |
Delayed rectifier K+ conductance [S/cm2] | 0.005 | 0.005 | 0.005 | 0.005 |
Ca2+-activated K+ conductance [S/cm2] | 0.003 | 0.00225 | 0.00075 | – |
AHP K+ conductance [S/cm2] | 0.0009 | – | 0.000225 | 0.000225 |
M-type K+ conductance [S/cm2] | 0 | 0.0023 | 0.00023 | 0.000023 |
L-type Ca2+ conductance [S/cm2] | 0.0014 | 0.0014 | – | – |
N-type Ca2+ conductance [S/cm2] | 0.0016 | 0.0016 | 0.0016 | 0.0016 |
T-type Ca2+ conductance [S/cm2] | 0.0005 | 0.0005 | 0.0005 | 0.0005 |
EL (mV) | -65 | -65 | -65 | -65 |
ENa (mV) | 50 | 50 | 50 | 50 |
EK (mV) | -80 | -80 | -80 | -80 |