Figure 4

Cell Interactions Over Time. Representative plot of fraction of cells adhered to another cell during a model run. Tumor cells bind with platelets (TC-Plt, purple) initially, followed by adhesion to endothelial cells (TC-EC, blue) and circulating or rolling neutrophils (TC-PMN, green). Rolling neutrophils simultaneously adhere with endothelial cells (PMN-EC, red). Stable tumor cell adhesion is achieved after 750 steps.