Table 5 Benchmarking the newly developed plug-and-play modeling tool against commonly used and established tools
From: A new flexible plug and play scheme for modeling, simulating, and predicting gastric emptying
| No. | Requirements | Proposed tool | COPASI/SimBiology | PhysioDesigner |
|---|---|---|---|---|
| 1 | Organ level modeling, and simulation | Models and simulates at organ level | Models and simulates at cellular level | Models and simulates at organ level |
| 2 | Lesser programing effort for: | Programing effort for: | Programing effort for: | Uses ISML (standard programing language) |
| and thus requires programing effort. | ||||
| 1. Structural description | 1. Structural description: No | 1. Structural description: No | ||
| 2. Functional description | 2. Functional description: | 2. Functional description: | ||
| single time effort, and reusable | No (COPASI, but not reusable); single time effort and reusable (SimBiology) | |||
| 3. Experimental data | 3. Experimental data: No | 3. Experimental data: No | ||
| 3 | User interface for model structural description | Textual thus machine readable and adaptable | Graphical | Graphical |
| (components and interconnections) | ||||
| 4 | Dynamic* model construction * Adaptive to experimental data collected, and structural change requests in time | Dynamic model construction is possible | Dynamic model construction is not possible | Dynamic model construction is not possible |
| 5 | Experimental data suppliable at the level of | Possible without any additional interface | Not possible without additional interface | Not possible without additional interface |
| physiological entities constituting the model |