From: A new flexible plug and play scheme for modeling, simulating, and predicting gastric emptying
No. | Requirements | Proposed tool | COPASI/SimBiology | PhysioDesigner |
---|---|---|---|---|
1 | Organ level modeling, and simulation | Models and simulates at organ level | Models and simulates at cellular level | Models and simulates at organ level |
2 | Lesser programing effort for: | Programing effort for: | Programing effort for: | Uses ISML (standard programing language) |
 |  |  |  | and thus requires programing effort. |
 | 1. Structural description | 1. Structural description: No | 1. Structural description: No |  |
 | 2. Functional description | 2. Functional description: | 2. Functional description: |  |
 |  | single time effort, and reusable | No (COPASI, but not reusable); single time effort and reusable (SimBiology) |  |
 | 3. Experimental data | 3. Experimental data: No | 3. Experimental data: No |  |
3 | User interface for model structural description | Textual thus machine readable and adaptable | Graphical | Graphical |
 | (components and interconnections) |  |  |  |
4 | Dynamic* model construction * Adaptive to experimental data collected, and structural change requests in time | Dynamic model construction is possible | Dynamic model construction is not possible | Dynamic model construction is not possible |
5 | Experimental data suppliable at the level of | Possible without any additional interface | Not possible without additional interface | Not possible without additional interface |
 | physiological entities constituting the model |  |  |  |