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Figure 2 | Theoretical Biology and Medical Modelling

Figure 2

From: Quantitative indices of autophagy activity from minimal models

Figure 2

Development of the experimental context-specific quantitative autophagy indices from the minimal model. The workflow of the process is as follows: 1. Establishment of the minimal autophagy model for the target autophagy system. 2. Reconstruction of underlying dynamics of the autophagic process at good time resolution. 3. Introduction of two quantitative autophagy indices measuring autophagy activity based on the model-driven autophagy profile. 4. Computer-aided analysis of the biological data with the help of the indices. 5. Specific/quantitative interpretation and system-level understanding of the system.

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