From: Beneficial effects of inhaled NO on apoptotic pneumocytes in pulmonary thromboembolism model
0 h | 2 h | 4 h | 6 h | |
---|---|---|---|---|
HR (beats/min) | ||||
Group 1 | 152 ± 5 | 155 ± 7 | 154 ± 8 | 157 ± 8 |
Group 2 | 155 ± 7 | 158 ± 6 | 156 ± 9 | 160 ± 7 |
Group 3 | 155 ± 5 | 162 ± 5*# | 168 ± 9*#Δ | 175 ± 8* |
Group 4 | 154 ± 6 | 160 ± 6 | 168 ± 8*Δ | 167 ± 7* |
pH | ||||
Group 1 | 7.32 ± 0.06 | 7.33 ± 0.03 | 7.29 ± 0.10 | 7.31 ± 0.01 |
Group 2 | 7.25 ± 0.04 | 7.26 ± 0.04 | 7.24 ± 0.03 | 7.21 ± 0.01 |
Group 3 | 7.25 ± 0.11# | 7.11 ± 0.18 | 7.23 ± 0.05 | 7.15 ± 0.14# |
Group 4 | 7.27 ± 0.05 | 7.18 ± 0.19 | 7.13 ± 0.11# | 7.15 ± 0.20 |
PaCO2 (mmHg) | ||||
Group 1 | 36.88 ± 6.06 | 41.52 ± 12.41 | 40.18 ± 13.86 | 40.84 ± 10.62 |
Group 2 | 38.88 ± 6.66 | 42.52 ± 12.41 | 42.18 ± 10.86 | 44.84 ± 7.62 |
Group 3 | 41.43 ± 9.51 | 56.77 ± 22.75 | 49.15 ± 14.03 | 47.48 ± 14.15 |
Group 4 | 38.88 ± 6.66 | 48.52 ± 22.41 | 45.18 ± 13.86 | 47.84 ± 17.62 |
PaO2/FiO2(mmHg) | ||||
Group 1 | 484.42 ± 28.34 | 475.50 ± 20.80 | 543.45 ± 61.56 | 423.20 ± 23.20 |
Group 2 | 430.95 ± 28.37 | 428.75 ± 37.50 | 431.25 ± 39.24◆ | 435.00 ± 31.62◆ |
Group 3 | 410.40 ± 28.36 | 335.55 ± 29.29*#Δ | 287.90 ± 54.84*#Δ | 292.83 ± 60.34*#Δ |
Group 4 | 441.43 ± 24.26 | 371.87 ± 20.35*# | 368.83 ± 55.29*#Δ◆ | 380.63 ± 56.83◆ |
MPAP (mmHg) | ||||
Group 1 | 14 ± 1 | 14 ± 1 | 13 ± 3 | 12 ± 1 |
Group 2 | 16 ± 2 | 15 ± 2 | 14 ± 1 | 15 ± 2 |
Group 3 | 17 ± 3 | 24 ± 4*#Δ | 22 ± 4#Δ | 18 ± 4#§ |
Group 4 | 17 ± 4 | 19 ± 3#Δ◆ | 20 ± 2#Δ | 15 ± 2#§ |
CO(l/min) | ||||
Group 1 | 2.95 ± 0.32 | 2.84 ± 0.24 | 2.84 ± 0.69 | 2.86 ± 0.53 |
Group 2 | 2.60 ± 1.00 | 2.62 ± 1.04 | 2.62 ± 1.08 | 2.73 ± 1.03 |
Group 3 | 2.88 ± 1.04 | 2.60 ± 1.14 | 2.71 ± 1.28 | 2.63 ± 1.19 |
Group 4 | 3.01 ± 0.64 | 2.62 ± 0.26 | 3.17 ± 0.54 | 3.20 ± 0.55 |
PVR(dyne.s.cm-5) | ||||
Group 1 | 164.24 ± 45.61 | 200.94 ± 59.54 | 140.46 ± 55.84 | 171.59 ± 38.72 |
Group 2 | 301.25 ± 96.77# | 253.68 ± 99.09 | 299.52 ± 92.64# | 271.66 ± 93.89# |
Group 3 | 373.20 ± 89.09# | 601.01 ± 92.33*#Δ | 435.88 ± 99.63# | 327.09 ± 96.66#§ |
Group 4 | 335.88 ± 63.46# | 474.67 ± 87.91*# | 335.93 ± 43.84# | 239.86 ± 53.26*◆§ |