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Table 1 HR, arterial blood gases and hemodynamic parameters at each time point after surgical procedures in four groups are shown (n = 6 in each group) x ¯ ± s

From: Beneficial effects of inhaled NO on apoptotic pneumocytes in pulmonary thromboembolism model

 

0 h

2 h

4 h

6 h

HR (beats/min)

    

Group 1

152 ± 5

155 ± 7

154 ± 8

157 ± 8

Group 2

155 ± 7

158 ± 6

156 ± 9

160 ± 7

Group 3

155 ± 5

162 ± 5*#

168 ± 9*#Δ

175 ± 8*

Group 4

154 ± 6

160 ± 6

168 ± 8

167 ± 7*

pH

    

Group 1

7.32 ± 0.06

7.33 ± 0.03

7.29 ± 0.10

7.31 ± 0.01

Group 2

7.25 ± 0.04

7.26 ± 0.04

7.24 ± 0.03

7.21 ± 0.01

Group 3

7.25 ± 0.11#

7.11 ± 0.18

7.23 ± 0.05

7.15 ± 0.14#

Group 4

7.27 ± 0.05

7.18 ± 0.19

7.13 ± 0.11#

7.15 ± 0.20

PaCO2 (mmHg)

    

Group 1

36.88 ± 6.06

41.52 ± 12.41

40.18 ± 13.86

40.84 ± 10.62

Group 2

38.88 ± 6.66

42.52 ± 12.41

42.18 ± 10.86

44.84 ± 7.62

Group 3

41.43 ± 9.51

56.77 ± 22.75

49.15 ± 14.03

47.48 ± 14.15

Group 4

38.88 ± 6.66

48.52 ± 22.41

45.18 ± 13.86

47.84 ± 17.62

PaO2/FiO2(mmHg)

    

Group 1

484.42 ± 28.34

475.50 ± 20.80

543.45 ± 61.56

423.20 ± 23.20

Group 2

430.95 ± 28.37

428.75 ± 37.50

431.25 ± 39.24

435.00 ± 31.62

Group 3

410.40 ± 28.36

335.55 ± 29.29*#Δ

287.90 ± 54.84*#Δ

292.83 ± 60.34*#Δ

Group 4

441.43 ± 24.26

371.87 ± 20.35*#

368.83 ± 55.29*#Δ

380.63 ± 56.83

MPAP (mmHg)

    

Group 1

14 ± 1

14 ± 1

13 ± 3

12 ± 1

Group 2

16 ± 2

15 ± 2

14 ± 1

15 ± 2

Group 3

17 ± 3

24 ± 4*#Δ

22 ± 4

18 ± 4

Group 4

17 ± 4

19 ± 3

20 ± 2

15 ± 2

CO(l/min)

    

Group 1

2.95 ± 0.32

2.84 ± 0.24

2.84 ± 0.69

2.86 ± 0.53

Group 2

2.60 ± 1.00

2.62 ± 1.04

2.62 ± 1.08

2.73 ± 1.03

Group 3

2.88 ± 1.04

2.60 ± 1.14

2.71 ± 1.28

2.63 ± 1.19

Group 4

3.01 ± 0.64

2.62 ± 0.26

3.17 ± 0.54

3.20 ± 0.55

PVR(dyne.s.cm-5)

    

Group 1

164.24 ± 45.61

200.94 ± 59.54

140.46 ± 55.84

171.59 ± 38.72

Group 2

301.25 ± 96.77#

253.68 ± 99.09

299.52 ± 92.64#

271.66 ± 93.89#

Group 3

373.20 ± 89.09#

601.01 ± 92.33*#Δ

435.88 ± 99.63#

327.09 ± 96.66

Group 4

335.88 ± 63.46#

474.67 ± 87.91*#

335.93 ± 43.84#

239.86 ± 53.26*§

  1. Note: Group 1: Sham group, Group 2: Ischemia group, Group 3: Reperfusion group, Group 4: Inhaled NO group. * and § P < 0.05 for the comparison with the parameters recorded at the time point before reperfusion and 2 hours after reperfusion within the same group, respectively. At the same time point among different groups,#P < 0.05 for the comparison with the Sham group,Δ P < 0.05 for the comparison with the Ischemia group, P < 0.05 for the comparison with the Reperfusion group.