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Table 3 GO annotation for genes co-identified by mRMR and shortest-path analysis

From: Computational identification of surrogate genes for prostate cancer phases using machine learning and molecular network analysis

Term

Genes

Count

%*

GO: 0043565 ~ sequence-specific DNA binding

ZNF148, ESR1, NR3C2, MYEF2

4

36. 364

GO: 0030528 ~ transcription regulator activity

ZNF148, UBC, ESR1, NR3C2, MYEF2

5

45. 455

GO: 0010604 ~ positive regulation of macromolecule metabolic process

ZNF148, UBC, ESR1, GJA1

4

36. 364

GO: 0010647 ~ positive regulation of cell communication

UBC, ESR1, GJA1

3

27. 273

GO: 0003700 ~ transcription factor activity

ZNF148, ESR1, NR3C2, MYEF2

4

36. 364

GO: 0003707 ~ steroid hormone receptor activity

ESR1, NR3C2

2

18. 182

GO: 0004879 ~ ligand-dependent nuclear receptor activity

ESR1, NR3C2

2

18. 182

GO: 0005496 ~ steroid binding

ESR1, NR3C2

2

18. 182

GO: 0010628 ~ positive regulation of gene expression

ZNF148, UBC, ESR1

3

27. 273

GO: 0005198 ~ structural molecule activity

VIM, UBC, TUBB6

3

27. 273

  1. *“%” refers to the percentage of genes in the total gene set.