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Figure 3 | Theoretical Biology and Medical Modelling

Figure 3

From: Pathway landscapes and epigenetic regulation in breast cancer and melanoma cell lines

Figure 3

The global network resulted from the union of transcriptional and post-transcriptional networks in MCF7. Node color: blue for up-regulated genes while yellow for down-regulated genes; Node border color: dark brown indicates the significant TFs inhibited and blue for TF activated among differentially expressed genes (with p-value<0.05) and the non-colored nodes correspond to TFs that regulate at least one target of the epigenetically modified genes from TFactS analysis.

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