Figure 4
From: Pathway landscapes and epigenetic regulation in breast cancer and melanoma cell lines
The global network resulted from the union of transcriptional and post-transcriptional networks in A375. Node color: red for up-regulated genes while green for down-regulated genes; Node border color: green indicates the significant TFs inhibited and red for TF activated among differentially expressed genes (with p-value<0.05) and the non-colored nodes correspond to TFs that regulate at least one target of the epigenetically modified genes from TFactS analysis.