Table 1 The common pathways associated to up-regulated genes.
From: Pathway landscapes and epigenetic regulation in breast cancer and melanoma cell lines
Type CCL | Pathway name | Genes | p-value | q-value |
|---|---|---|---|---|
BC | Atm signaling | ATM; MDM2; RBBP8; JUN; TP73 | 2.81E-06 | 7.96E-04 |
Melanoma | Â | JUN; TP73 | 5.73E-03 | 3.42E-02 |
BC | Colorectal cancer | JUN; TGFB3; RAF1; DCC | 9.04E-03 | 6.89E-02 |
Melanoma | Â | MSH2; JUN; DCC; TCF7L2 | 6.36E-04 | 1.45E-02 |
BC | DNA repair | XPC; LIG3; ATM; TDG; ERCC6; FANCE; FANCC; RAD50 | 1.30E-04 | 9.17E-03 |
Melanoma | Â | MUTYH; POLD1; TDG; FANCA | 5.94E-03 | 3.42E-02 |
BC | Extracellular matrix organization | MMP14; TGFB3; ADAM17; CTSG; COL1A2; MMP8; CTSL2 | 4.01E-03 | 5.02E-02 |
Melanoma | Â | COL3A1; COL1A2; ITGB4; TIMP1; COL1A1 | 2.78E-03 | 2.38E-02 |
BC | Hemostasis | IGF2; PRKCH; PPP2R1B; TGFB3; AKAP1; SERPINC1; VAV2; PRKCE; ANGPT2; GNA12; GNA13; ABCC4; RAF1 | 9.01E-03 | 6.89E-02 |
Melanoma | Â | IGF2; TIMP1; SERPINC1; CD47; PRKCE; GRB7; PDPK1; ITPR3 | 9.42E-03 | 4.30E-02 |
BC | Hippo signaling | WNT2B; PPP2R1B; TGFB3; WNT1; ID2; TP73; TEAD4 | 4.62E-03 | 5.02E-02 |
Melanoma | Â | DVL3; LATS1; FZD4; TP73; TCF7L2 | 3.11E-03 | 2.50E-02 |