Sitea | NetPhosb | Scansitec | 2Dd | Surface Accessibilitye |
---|
 | MYH1 | MYH4 | MYH2 | MYH8 | MYSS_CHICK | MYH3_CHICK | MYH3 | MYH1 | MYH4 | MYH2 | MYH8 | MYSS_CHICK | MYH3_CHICK | MYH3 | MYH1 | 1BR2 | 1B7T:A | 2MYS: A | Mean |
---|
47 | - | - | - | Y | Â | Â | Â | - | - | - | Â | Â | Â | Â | E(4) | (14.5) | (21) | (16) | 18.5 |
54 | - | - | - | - | - | - | Y | - | - | - | - | - | - | Â | E(7) | Â | (52) | (60) | 56.0 |
85 | Y | Y | Y | Y | Y | Y | Y | Â | Â | Â | Â | Â | Â | Â | C(2) | (34.7) | (28) | 16 | 26.2 |
163 | Y | Y | Y | Y | Y | Y | Y | YP | YP | YP | YP | YP | YP | YP | H(9) | 13.3 | 47 | 8 | 22.8 |
286 | Y | Y | Y | Y | Y | Y | Y | Â | Â | Y | Y | Â | Â | Â | H(7) | (0) | 0 | 0 | 0.0 |
313 | Y | - | Â | Â | Â | Â | Â | YP | - | Y | Y | YP | Y | Y | C(4) | 7 | 5 | 8 | 6.7 |
413 | Y | Y | Y | Y | - | Y | Y | Â | Â | Â | Â | - | Â | Â | E(7) | Â | Â | (68) | 68.0 |
435 | Â | Â | Â | Â | Â | - | Y | Â | Â | Â | Â | Â | - | Â | H(9) | (0.7) | 4 | 3 | 2.6 |
504 | Y | Y | Y | Y | Y | Y | Y | Â | Â | Â | Â | Â | Â | Â | H(9) | 0 | 6 | 9 | 5.0 |
719 | Y | Y | Y | Y | Y | Â | Â | YP | YP | YP | YP | YP | YP | Y | H(6) | (21.8) | 19 | 9 | 16.6 |
1379 | Y | Y | Y | Y | Y | Y | Y | Â | Â | Â | Â | Â | Â | Â | H(6) | Â | Â | Â | Â |
1464 | - | Y | - | Y | Y | Y | - | - | Â | - | Â | Â | Â | - | H(7) | Â | Â | Â | Â |
1492 | Y | Y | Y | Y | Y | Y | Y | Â | Â | Â | YP | Â | Â | P | H(6) | Â | Â | Â | Â |
1856 | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y | H(4) | Â | Â | Â | Â |
- a. Sites are numbered relative to the MHC sequence MYH1_HUMAN/P12882.
- b. Y indicates predicted tyrosine phosphorylation site in all the sequences of orthologous group, with a score of ≥ 0.8 in at least one human sequence. Dashes indicate lack of a tyrosine in that position.
- c. Y indicates predicted tyrosine phosphorylation site in all the sequences of orthologous group on 'Low Stringency'. P indicates predicted phosphotyrosine recognition site in all the sequences of orthologous group on 'Low Stringency'. Dashes indicate lack of a tyrosine in that position.
- d. PSIPRED (McGuffin, Bryson and Jones 2000) secondary structure position for MYH1_HUMAN. Letters indicate predicted secondary structure (H = helix, E = strand, C = coil). Numbers in brackets are confidence measures (0 = low, 9 = high).
- e. Surface accessibility figures are "numbers of water molecules in contact with this residue *10, or residue water exposed surface in Angstrom**2" (Kabsch and Sander 1983). Missing values indicate residues missing from the PDB structure. Values in brackets indicate residues that are not tyrosines in the PDB structure.