Figure 3

Relationship between voltage shift of persistent sodium channels relative to transient sodium channels and the shape of the action potential. For voltage shifts of -10 mV and -0 mV, the number of persistent sodium channels is set to a value (3.75% and 15%, respectively) that would produce approximately the same degree of breakdown of accommodation as the default model (voltage shift of -20 mV). A) The shape of the action potentials. B) The accommodation curves for the three voltage shifts of -20 mV●, -10 mV■, and -0 mV▲.