Skip to main content

Table 1 The genes of the (+)-training set (without orthologs). Marked with asterisks are those included in the "seed" set.

From: Construction of predictive promoter models on the example of antibacterial response of human epithelial cells

No

Gene name

Accessin no. And LocusLinkID

Experimental evidence

Additional information

Participation in anti-Pseudomonas response

1

Monocyte chemoattractant protein-1, MCP-1*

EMBL: D26087

Microarray [66], other experiments [20,21,38]

Is well know as expressed in antibacterial response

100%

2

β-defensin*

LocusLinkID: 1673

[15,18,19,39,40]

Is well known as expressed in antibacterial response; important target gene in innate immunity

100%

3

Interferon regulatory factor 1, IRF-1*

LocusLinkID: 3659

Microarray [66]

Known to be expressed in epithelial cells

probable

4

Equilibrate nucleoside transporter 1, SLC29a1

LocusLinkID: 2030

Microarray [66]

  

5

Proteinkinase C η type, PKCη*

LocusLinkID: 5583

Microarray [66] TRANSPATH®

Important link in Ca2+-connected pathways

probable

6

Folypolyglutamate synthase, FPGS

Ensembl : ENSG00000136877

Microarray [66]

  

7

RhoB*

LocusLinkID: 388

Microarray [66]

is induced as part of the immediate early response in different systems

probable

8

Origin recognition complex subunit 2, hORC2L

LocusLinkID: 4999

Microarray [66]

  

9

Transcription factor TEL2*

LocusLinkID: 51513

Microarray [66]

Transcription factor

probable

10

Interleukin 8, IL8*

EPD: EP73083 LocusLinkID: 3576

[10,11,26,44,45]

Is well know as expressed in antibacterial response

100%

11

Transcription factor ELF3*

LocusLinkID: 1999

Microarray [66]

Transcription factor

probable

12

Mucin 1(mouse gene), MUC1*

RefSeq: NM_013605

[17,27,28,36,47]

Different mucins are shown as expressed in antibacterial response

100%

13

NF-kappaB inhibitor alpha, IkBa*

LocusLinkID: 4792 EPD: EP73215

Microarray [66]

NF-kB inhibitor, the main link in NF-kB-targeting pathways

Very high

14

Tissue Factor Pathway Inhibitor 2, TFPI

LocusLinkID: 7980 EPD: EP73430

Microarray [66]

  

15

Urokinase-type plasminogen activator precursor, PLAU

LocusLinkID: 5328

Microarray [66]

  

16

c-jun*

 

Microarray [66]

Transcription factor

probable

17

Cytochrom P450 dioxin-inducible*

LocusLinkID: 1545

Microarray [66]

Stress-inducible

probable

18

Dyphtheria toxin resistance protein, DPH2L2

EPD: EP74285

Microarray [66]

  
Back to article page

Theoretical Biology and Medical Modelling

ISSN: 1742-4682