Figure 4

Model replicates published data. A, B, The model's simulation of Mulder et al.'s sampling [39], assuming γ has the beta distribution on the interval [0.8060, 0.9612] with both shape parameters equal to 1.5. The platelet 5-HT levels were calculated by using equation (3), with the values of K, F _C , R _C , α _normal and α _autistic taken from Table 1. C, D, The actual data from Mulder et al. [39] (reprinted by permission from Lippincott Williams & Wilkins, modified). In the simulated and actual sampling, 60 normal and 33 autistic subjects were used. Note that the exact appearance of the histograms will vary from sampling to sampling due to the small number of cases in each bin.