Table 2 Predicted and observed ranges, means (<ser>), and standard deviations (SD) of platelet 5-HT levels, ser(α, γ). The distribution of γ was assumed to be continuously uniform; the theoretical SD values given in the table can be further improved by assuming that γ has a beta distribution or a normal distribution (see the text). Note that, strictly speaking, the model's <ser > and SD are precise theoretical expectations and standard deviations and, therefore, the notation μ ser (α, a, b) and σ ser (α, a, b) would be more accurate (but less convenient here).
From: Statistical distribution of blood serotonin as a predictor of early autistic brain abnormalities
| Â | Mulder et al. [39] (nmol/109 platelets) | Coutinho et al. [40] (ng/109 platelets) | McBride et al. [74] (ng/ml) | |||
|---|---|---|---|---|---|---|
| Â | Model | Observed | Model | Observed | Model | Observed |
Min normal | 1.42 | 0.67 | 0 | 66 | 75 | 85 |
Max normal | 5.57 | 5.67 | 598 | 676 | 417 | 449 |
< ser > normal | 3.66 | 3.58 | 320 | 260 | 252 | 230 |
SD normal | 1.19 | 1.08 | 172 | 137 | 99 | - |
Min autistic | 1.37 | 2.33 | 0 | 50 | 73 | 120 |
Max autistic | 8.18 | 8.33 | 925 | 1125 | 546 | 567 |
< ser > autistic | 4.58 | 4.51 | 414 | 304 | 294 | 287 |
SD autistic | 1.96 | 1.61 | 265 | 207 | 136 | - |