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Figure 5 | Theoretical Biology and Medical Modelling

Figure 5

From: Possible Cis-acting signal that could be involved in the localization of different mRNAs in neuronal axons

Figure 5

A model of the 3'-UTR/U-rich region by virtue of which the mRNA could be transported toward the axon. The mRNAs that contain a U-rich sequence in the 3'-UTR are candidates for transport toward the axon. The model suggests that an mRNA binding protein intreacts with the signal-sequence forming a putative complex that is anchored to a kinesin protein. The mRNAs that do not contain such a U-sequence might remain in the cell body or to migrate towards the dendrites.

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Theoretical Biology and Medical Modelling

ISSN: 1742-4682