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Figure 7 | Theoretical Biology and Medical Modelling

Figure 7

From: Modeling the signaling endosome hypothesis: Why a drive to the nucleus is better than a (random) walk

Figure 7

Representative trajectories for 22 random walk simulations using both diffusion and dephosphorylation criteria (red and blue lines), compared to the movement of a signaling endosome within the same 1 second time frame (green line). Parameters: 15 μm cell diameter, 5 μm nucleus diameter, 37°C, 1 sec, coefficient of diffusion and dephosphorylation probability as described in the text. Arrows along the plasma membrane surface denote the sites of signal initiation.

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