A mathematical model of the euglycemic hyperinsulinemic clamp

Table 1 Anthropometric and metabolic characteristics for lean (BMI ≤ 25) and overweight or obese (BMI > 25) subjects.

	Lean subjects (n = 7)	Overweight and Obese subjects (n = 8)	p
BMI [kg/m²]	20.0 [18.5, 22.7]	37.0 [27.8, 63.6]	0.001
BSA [m²]	1.55 [1.49, 1.73]	2.1 [1.83, 2.38]	0.001
G_fast [mM]	3.67 [3.4, 5.4]	5.2 [4.61, 5.9]	0.024
I_fast [pM]	27.8 [13.9, 49.4]	123.7 [79.2, 152.9]	0.001
I_max [pM]	482.14 [464.5, 526.9]	606.3 [497.3, 683.2]	0.004

Values are median [min, max]. All comparisons were performed by the Mann-Whitney U-test. BSA is the Body Surface Area [m²] calculated via the DuBois formula (BSA = 0.20247 · height ^0.725 [m] · weight ^0.425 [kg])

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