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Figure 3 | Theoretical Biology and Medical Modelling

Figure 3

From: Repolarization of the action potential enabled by Na+ channel deactivation in PSpice simulation of cardiac muscle propagation

Figure 3

Propagation of APs simulated by PSpice along a chain of ten cardiac muscle cells. The entire AP is depicted, but to avoid confusion the records illustrate only three of the cells: cells # 1, 5 and 10. The four panels show the effect of varying the number of gj-channels from zero (panel A, Rgj = 100,000 MΩ), to one (panel B, Rgj = 10,000 MΩ), to 10 (panel C, Rgj = 1,000 MΩ), to 1000 (panel D, Rgj = 10 MΩ). When there were many gj-channels (D), the APs of all 10 cells were superimposed, indicating extremely fast propagation velocity.

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