Figure 1From: Propagated repolarization of simulated action potentials in cardiac muscle and smooth muscleCardiac Muscle and Smooth Muscle. Circuit diagram used for study of propagated repolarization in cardiac muscle and smooth muscle. A: 5-cell chain. A depolarizing stimulating pulse (IS1; 0.50 ms, 0.25 nA) was applied to the inside of the first cell (A1; left side). A hyperpolarizing pulse (IS2; variable intensity and duration) was applied to the inside of the fifth cell (A5; right side) a few milliseconds later when the action potentials (APs) initiated by IS1 were in their plateau phase (peak overshoot). B: Enlarged diagram to show a portion of the circuit for details of the basic units.Back to article page