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Figure 3 | Theoretical Biology and Medical Modelling

Figure 3

From: A model for generating circadian rhythm by coupling ultradian oscillators

Figure 3

Behavior of the circadian oscillator under free-running conditions. The concentration of the homodimeric protein product D5 of the forced oscillator (gene 5 in Figure 1) shows both a small, residual short-period fluctuation and a low-frequency oscillation of much higher amplitude, with a period of 26.7 hours in constant darkness. The small, fast oscillations correspond to the average period of the primary oscillators (ca. 3 hours). The lighter (gray) trace represents the behavior of the model in which the primary transcriptional-feedback oscillators of the model are replaced by sine functions (equations 23 and 24). The variable plotted is SD5, representing the behavior of D5 when it is driven by the sine wave functions.

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