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Figure 1 | Theoretical Biology and Medical Modelling

Figure 1

From: Kinetic modeling of tricarboxylic acid cycle and glyoxylate bypass in Mycobacterium tuberculosis, and its application to assessment of drug targets

Figure 1

TCA cycle and glyoxylate bypass reactions considered in E. coli and M. tuberculosis models. Reactions 1, 2, 3, 5, 8, 9, 10, 11, 12 and 13 were present in all the models; reaction 4 was present only in the E. coli model and M. tuberculosis model-1, but absent from M. tuberculosis model-2; and reactions 6 and 7 were present in the M. tuberculosis models, but absent from E. coli model. 1, CS; 2, ACN; 3, ICD in E. coli model and ICD1 and ICD2 in M. tuberculosis models; 4, KDH; 5, ScAS; 6, KGD; 7, SSADH; 8, SDH; 9, FUM; 10, MDH; 11, fraction of αKG utilized for precursor biosynthesis (SYN); 12, ICL in E. coli model and ICL1 and ICL2 in M. tuberculosis models; 13, MS.

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