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Figure 2 | Theoretical Biology and Medical Modelling

Figure 2

From: Kinetic modeling of tricarboxylic acid cycle and glyoxylate bypass in Mycobacterium tuberculosis, and its application to assessment of drug targets

Figure 2

Effect on the flux through ICDs and ICLs with varying Vf ICD1 and Vf ICD2 . Effects of varying (A) VfICD1 alone, (B) both VfICD1 and VfICD2 simultaneously (abbreviated as VfICDs), (C) VfICD1 and VfICD2 simultaneously (abbreviated as VfICDs) with ICL1 reaction removed from the model to simulate deletion of gene encoding ICL1, (D) VfICD1 and VfICD2 simultaneously (abbreviated as VfICDs), with ICL2 reaction removed from the model to simulate deletion of gene encoding ICL2. Broken line represents the sum of flux through ICD1 and ICD2, and solid line represents the sum of flux through ICL1 and ICL2.

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Theoretical Biology and Medical Modelling

ISSN: 1742-4682