Skip to main content
Figure 3 | Theoretical Biology and Medical Modelling

Figure 3

From: Kinetic modeling of tricarboxylic acid cycle and glyoxylate bypass in Mycobacterium tuberculosis, and its application to assessment of drug targets

Figure 3

Competitive inhibition of ICLs by an inhibitor with concentration I and inhibitor constant K I . Inhibition of ICL1 and ICL2, with VfICD1 and VfICD2 both kept at (A) 2.5% of the original values, (B) 5% of the original values. Broken line represents the sum of flux through ICD1 and ICD2, and solid line represents the sum of flux through ICL1 and ICL2. The effect of inhibitor is shown by varying the ratio of I/KI.

Back to article page