Table 1 The four category model: risks and cases for a population of size N.
Category | Risk of being in category | Number of people in category | Number of cases in category |
|---|---|---|---|
ge (high-risk genotype/high-risk exposure) | Rge | γεN | γε RgeN |
go (high-risk genotype/low-risk exposure) | Rgo | γ (1-ε)N | γ (1-ε)RgoN |
oe (low-risk genotype/high-risk exposure) | Roe | ε (1-γ)N | ε (1-γ)RoeN |
oo (low-risk genotype/low-risk exposure) | Roo | (1-ε) (1-γ)N | (1-ε) (1-γ)RooN |
Total | Â | N | rtN |