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Table 1 The results of optimization for scenario A.

From: Identification of biomolecule mass transport and binding rate parameters in living cells by inverse modeling

  Initial guesses Optimized values       
run D f (μm2 s-1) K a * MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaacqWGlbWsdaqhaaWcbaGaemyyaegabaGaeiOkaOcaaaaa@301F@ (s-1) K d (s-1) D f (μm2 s-1) K a * MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaacqWGlbWsdaqhaaWcbaGaemyyaegabaGaeiOkaOcaaaaa@301F@ (s-1) K d (s-1) F eq C eq t b (ms) t d (ms) RMSE R 2
1 1.4 0.01 0.24 1.3454 0.0081 0.249 0.9685 0.0315 4016 123450 0.0241 0.9904
2 15 500 86 13.5563 806 83 0.0934 0.9066 12.00 1.2407 0.0233 0.9912
3 10 20 50 1.2689 22.88 538 0.9592 0.0408 1.90 44.00 0.0245 0.9903
4 1.26 3000 5 79.7179 1.06*104 168 0.0156 0.9844 6.00 9.00 0.0236 0.9910
5 12 30 490 1.8558 256 489 0.6564 0.3436 2.00 3.91 0.0244 0.9904
6 1.2 200 49 7.4289 200 42.5 0.1753 0.8247 23.50 5.00 0.0235 0.9911
7 7 2 470 1.2248 4.70 540.72 0.9914 0.0086 1.80 213.00 0.0245 0.993
8 0.7 202 0.047 6.6616 56.362 38.25 0.4043 0.5957 26.10 18.00 0.0235 0.9910
9 1.5 0.001 85 1.2127 7*10-5 91.21 1.000 0.000 11.00 15.00 0.0246 0.9902
10 1.5 0.1 1*10-5 1.2127 0.1874 1*10-5 0.0001 0.9999 200 5336 0.0245 0.9903
11 1.5 1*10-5 1 1.4652 0.1974 2.1902 0.9173 0.0827 456.6 5066 0.0251 0.9900
12 9.2 500 86.4 8.3315 468.56 83.38 0.1511 0.8489 12.00 2.00 0.0234 0.9911
13 25 0.001 100 1.2534 1.3557 44.94 0.9707 0.0293 22.30 738 0.0245 0.9903
14 0.25 0.001 100 1.2236 0.4235 119.71 0.9965 0.0035 8.40 2361 0.0245 0.9903
15 5 400 0.40 10.1911 396.8 56.7 0.1250 0.8750 17.60 2.52 0.0233 0.9911
16 15 4 1400 1.2205 3.81 1389 0.9973 0.0027 7.00 262 0.0245 0.9903
17 4.5 150 385 4.3970 986 380 0.2782 0.7218 2.60 1.00 0.0242 0.9905
18 10 150 385 8.861 2458 396 0.1388 0.8612 2.50 0.40 0.0242 0.9905
19 0.4 0.5 0.003 1.6371 0.5211 3.20 0.86 0.1400 312.50 1919 0.0254 0.9901
20# - - - 9.20 500 86.4 0.1474 0.8526 11.60 2.00 0.0255 0.9886
  1. # These values were obtained by Sprague et al. [14].