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Table 7 The results of parameter optimization for scenario C (estimation of two parameters in a FRAP experiment: D f - K a * MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaacqWGlbWsdaqhaaWcbaGaemyyaegabaGaeiOkaOcaaaaa@301F@ ).

From: Identification of biomolecule mass transport and binding rate parameters in living cells by inverse modeling

Estimate D f and K a * MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaacqWGlbWsdaqhaaWcbaGaemyyaegabaGaeiOkaOcaaaaa@301F@
Initial guesses Optimized values   
D f (μm2 s-1) K a * MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaacqWGlbWsdaqhaaWcbaGaemyyaegabaGaeiOkaOcaaaaa@301F@ (s-1) K d (s-1) D f (μm2 s-1) K a * MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaacqWGlbWsdaqhaaWcbaGaemyyaegabaGaeiOkaOcaaaaa@301F@ (s-1) K d (s-1) RMSE R 2
50 3 0.1108 3.8162 (6.9081) 4.1352 (7.2953) 0.1108 0.0042 (0.0104) 0.9997 (0.9983)
3 50 0.1108 47.7952 (35.6424) 47.5709 (35.8541) 0.1108 0.0003 (0.0102) 1.0000 (0.9984)
20 25 0.1108 25.2109 (25.2109) 25.2769 (25.2769) 0.1108 0.0001 (0.0001) 1.0000 (1.0000)
25 20 0.1108 24.5737 (24.5737) 24.6488 (24.6488) 0.1108 0.0002 (0.0002) 1.0000 (1.0000)
28 35 0.1108 34.8874 (34.8874) 34.8255 (34.8255) 0.1108 0.0001 (0.0001) 1.0000 (1.0000)
0.1 100 0.1108 89.9205 (89.9205) 89.1097 (89.1097) 0.1108 0.0005 (0.0005) 1.0000 (1.0000)
100 0.1 0.1108 8.5511 (8.5511) 8.8336 (8.8336) 0.1108 0.0017 (0.0017) 1.0000 (1.0000)
28 28 0.1108 28.2015 (28.2015) 28.2282 (28.2282) 0.1108 0.0001 (0.0001) 1.0000 (1.0000)
  1. The values in parentheses were obtained using corrupted data.