Table 4 Effects of variation in mSHMT and external glycine*
From: In silico experimentation with a model of hepatic mitochondrial folate metabolism
| Â | Normal | mSHMT = 0 | Extenal gly = 0 | mSHMT = 0 Extenal gly = 0 |
|---|---|---|---|---|
cellular glycine | 1087 | 1046 | 272 | 123 |
flux of glycine from mitochondria to cytosol | -451 | -474 | +90 | -67 |
velocity of mSHMT | 84 | 0 | 868 | 0 |
velocity of cSHMT | 9.2 | 19 | 114 | 218 |
flux of HCOOH to cytosol | 546 | 524 | 538 | 245 |