fs(Pre) | Ω(Pre)-> Ω(Post) | ω(Pre)->ω(Post) | fs(Post) |
---|
1.0 | 3->0 | 1->1 | .50 |
1.0 | 3->1 | 2->2 | .77 |
1.0 | 3->1 | 2->1 | .50 |
1.0 | 3->2 | 3->2 | .77 |
1.0 | 3->2 | 3->3 | .92 |
.85 | 3->2 | 3->3 | .74 |
.85 | 3->2 | 3->2 | .57 |
- The term fs(Pre) is the survival fraction of a tumor cell's population prior to the application of a targeted therapy; Ω(Pre)-> Ω(Post) represents the change in transformed states resulting from oncogene inhibition ; ω(Pre)->ω(Post) represents the change in differentiation states resulting from oncogene inhibition. The term fs(Post) is the survival fraction or reduced proliferation of a tumor cell population that results from oncogene inhibition and is calculated from equation (7).