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Figure 6 | Theoretical Biology and Medical Modelling

Figure 6

From: A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies

Figure 6

APC -dependent growth regulation. Top: Evolution of the number of quiescent cells and total number of cells over time (log plot). Cell population is regulated through APC activation owing to overpopulation. Total cell number (continuous line) and number of quiescent cells (dotted line). Bottom: Snapshots of cells within the computational domain during simulation (t = 100 h). Left: Total cell number. Right: Mitotic cells are only in the outer region of the tumor masses. Cells at the core are quiescent through APC activation due to overpopulation.

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