Figure 10
From: Computer simulation analysis of normal and abnormal development of the mammalian diaphragm
Initial conditions. Nudge++™ images of the initial PPF cell population, based on data from transverse sections of the E11.5 mouse embryo. The right side of each image models normal development; the left side models the precursor defect in the PPF and CDH development (see text and Fig. 4). The color scheme is determined by which cellular state the user chooses to observe. Pictured here is the same E11.5 simulation starting point with cells color-tagged based on (A) PPF of origin (purple = right, blue = left), (B) cell-cycle phase (blue = G1, green = S, turquoise = G2, red = M), and (C) polyclone (green = anterior PPF, yellow = posterior PPF).