Figure 9

Morphing of anatomical region boundary data over simulation time. Shown are four images of cross-sectional tissue outlines in the model embryo and representing a transition from E11.5 to E13. Images are shown at 12 hour intervals (E11.5, E12, E12.5, and E13). Tissues outlined include the body wall (green), dorsal mesentery (yellow), PPF (white) and aorta (red). The tissue outlines in the E11.5 and E13 images are directly digitized from experimental material (see Fig. 7 and 8). The intermediate images are calculated by morphing between these two endpoints; short arrows indicate direction of body wall growth. Although only two intermediate images are shown, the program calculates new tissue outlines continuously as the simulation progresses. Those for the body wall and dorsal mesentery act as absolute boundaries to cell movement; the body wall has trophic and tropic effects in some simulations (see text).