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Table 1 Numerical values of the parameters that are fixed throughout all scenarios

From: A mathematical model separates quantitatively the cytostatic and cytotoxic effects of a HER2 tyrosine kinase inhibitor

parameter numerical value remarks
a G 1 MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaacqWGHbqydaWgaaWcbaGaem4raC0aaSbaaWqaaiabigdaXaqabaaaleqaaaaa@3062@ 7 h G1/S-boundary in absence of drugs
a S 11 h S/G2-boundary in absence of drugs
a m 15 h minimal age for division
a M 30 h maximal cell age
σ 2 standard deviation of intermitotic times
c 0.22 nonproliferation constant
M 0 6·105 cells crowding threshold for nonproliferation
μ(a) {1, 0.25, 0.6} see Figure 6 B