Table 2 Estimated patterns in distinguishing dynamic from static enzymes.
From: Distinguishing enzymes using metabolome data for the hybrid dynamic/static method
E. coli | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
w | 1.000 | Â | 0.750 | Â | 0.500 | Â | 0.250 | Â | 0.100 | Â | 0.075 | Â | 0.050 | Â | 0.025 | Â | 0.010 | Â |
Noise | - | + | - | + | - | + | - | + | - | + | - | + | - | + | - | + | - | + |
Fitness (-) | 7.83 × 10-1 | 3.37 | 7.13 × 10-1 | 3.30 | 6.42 × 10-1 | 3.23 | 5.71 × 10-1 | 3.16 | 5.06 × 10-1 | 3.09 | 4.94 × 10-1 | 3.08 | 4.82 × 10-1 | 3.07 | 4.69 × 10-1 | 3.05 | 4.59 × 10-1 | 3.04 |
PGI | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | D | D | D |
PFK | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
ALDO | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
TIS | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S |
GAPDH | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
PGK | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
PGluMu | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
ENO | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
PK | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
PGM | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | D | D | D |
G6PDH | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
PGDH | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
Ru5P | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | D |
R5PI | S | S | S | S | S | S | D | S | D | D | D | D | D | D | D | D | D | D |
TKa | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | D | S |
TKb | S | S | S | S | S | S | D | D | D | D | D | D | D | D | D | D | D | D |
TA | S | S | S | S | S | S | S | S | D | D | D | D | D | D | D | S | D | S |
S. cerevisiae | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
w | 1000 | Â | 0.750 | Â | 0.500 | Â | 0.250 | Â | 0.100 | Â | 0.075 | Â | 0.050 | Â | 0.025 | Â | 0.010 | Â |
Noise | - | + | - | + | - | + | - | + | - | + | - | + | - | + | - | + | - | + |
Fitness (-) | 3.35 × 10-1 | 1.75 × 101 | 2.64 × 10-1 | 1.75 × 101 | 1.94 × 10-1 | 1.74 × 101 | 1.10 × 10-1 | 1.73 × 101 | 5.42 × 10-2 | 1.73 × 101 | 4.17 × 10-2 | 1.73 × 101 | 4.17 × 10-2 | 1.73 × 101 | 1.68 × 10-2 | 1.72 × 101 | 8.02 × 10-3 | 1.72 × 101 |
PGI | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
PFK | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
ALDO | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
TIS | S | S | S | D | S | D | D | D | D | D | D | D | D | D | D | D | D | D |
GAPDH | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
PGK | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
PGluMu | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
ENO | D | S | D | S | D | S | D | S | D | S | D | S | D | S | D | S | D | S |
PK | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
PGM | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | D | S |
G6PDH | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
PGDH | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S |
Ru5P | S | S | S | S | S | S | S | D | D | D | D | D | D | D | D | D | D | D |
R5PI | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | D | D |
TKa | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S |
TKb | S | S | S | S | S | S | S | S | D | S | D | S | D | S | D | S | D | S |
TA | S | S | S | S | S | S | S | S | S | S | S | S | S | D | S | D | D | D |