Figure 4
Upper panel: The complete set of the ratios of the fourth (T4) to the first twitch (T1) as a function of the concomitant T1 observed in a single subject. The dose of vecuronium was 25 μg·kg-1. The grid of the 11 curves is that presented in Figure 3. The dashed line parallel with the Y-axis indicates the minimal T1. Lower panel: The observed values of T4/T1 were interpolated between the [A]4/[A]1 curves to obtain [A]4/[A]1 values at times of the observed T4/T1-T1 data pairs. The estimated [A]4/[A]1 values are plotted as a function of time elapsed from the injection of vecuronium. The time-course of T1 depression in the same subject is also plotted (right Y-axis, filled circles). The dashed line parallel with the Y-axis indicates the time of the minimal T1.